Like other berries, cranberries contain antioxidant polyphenols. However, most of these antioxidants are in the skin of the cranberry. Therefore, cranberry juice doesn’t contain as many polyphenols. The best-known health benefit of cranberries is their ability to reduce the risk of urinary tract infections (UTIs. Certain chemicals in cranberries prevent the bacteria E. coli from sticking to the wall of the bladder or urinary tract, therefore reducing the risk of infection. A number of studies have shown that drinking cranberry juice or taking cranberry supplements can reduce the risk of UTIs Cranberry juice may reduce the risk of other infections as well.